Accelerating Academic Researchers

FIDA measures binding kinetics directly in solution, providing a more accurate representation of how molecules behave in their natural state, avoiding the cumbersome workflow of traditional surface-based techniques. The result is precise, easily interpretable, “artefact-free” data on binding affinities and kinetic rates that reflect actual biological conditions. Furthermore, by measuring the absolute size of molecules in solution, FIDA enables monitoring a range of integrity parameters, incl. conformational changes, oligomeric state and protein aggregation—three critical factors influencing drug efficacy and stability.

FIDA excels at measuring interactions across a wide concentration range (pM to mM), fromsmall molecules to large biomolecules. This flexibility is crucial for drug discovery teamswho need to test molecules at varying concentrations without losing sensitivity. Whetherscreening for early hits, optimizing lead compounds, or predicting drug developability, FIDAdelivers the precision needed to confidently assess binding affinity, even in low-concentrationsamples.

Traditional methods often require the use of labels or modifications that can interfere with the natural properties of the drug target. With a wide array of detectors available, Fida can operate label-free, preserving the integrity of proteins and other biomolecules. This allows for more reliable data when investigating protein-ligand interactions, which is especially important in the development of biologics where maintaining the natural structure is key

FIDA delivers absolute, high-quality binding constants, kinetics and interaction data , ensuring reproducibility and accuracy—perfect for peer-reviewed journals and grant applications.

FIDA’s intuitive interface and quick setup mean that even students can master the technology, reducing the training burden on senior researchers and faculty. Furthermore, its clog-free design ensures minimal downtime, meaning your department's research schedule stays on track without costly interruptions.